Using steered molecular dynamics to predict and assess Hsp70 substrate-binding domain mutants that alter prion propagation.

Xu, L and Hasin, N and Shen, M and He, J and Xue, Y and Zhou, X and Perrett, S and Song, Y and Jones, GW (2013) Using steered molecular dynamics to predict and assess Hsp70 substrate-binding domain mutants that alter prion propagation. PLoS computational biology, 9 (1). e1002896. ISSN 1553-734X DOI: https://doi.org/10.1371/journal.pcbi.1002896

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Divisions: Faculty of Health and Social Sciences > School of Clinical and Applied Sciences
Identification Number: https://doi.org/10.1371/journal.pcbi.1002896
Status: Published
Refereed: Yes
Uncontrolled Keywords: Prions; Protein Binding; Mutation; Hydrogen Bonding; Models, Molecular; HSP70 Heat-Shock Proteins; Molecular Dynamics Simulation
Date Deposited: 14 Mar 2016 09:45
Last Modified: 19 Nov 2018 10:29
Item Type: Article

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