Items where Author is "Owens, RA"

Downes, SG and Owens, RA and Walshe, K and Fitzpatrick, DA and Dorey, A and Jones, GW and Doyle, S (2023) Gliotoxin-mediated bacterial growth inhibition is caused by specific metal ion depletion. Scientific Reports, 13. pp. 1-20. ISSN 2045-2322 DOI: https://doi.org/10.1038/s41598-023-43300-w

Downes, SG and Doyle, S and Jones, GW and Owens, RA (2023) Gliotoxin and related metabolites as zinc chelators: implications and exploitation to overcome antimicrobial resistance. Essays in Biochemistry. pp. 1-12. ISSN 1744-1358 DOI: https://doi.org/10.1042/EBC20220222

Traynor, AM and Owens, RA and Coughlin, CM and Holton, MC and Jones, GW and Calera, JA and Doyle, S (2021) At the metal-metabolite interface in Aspergillus fumigatus: towards untangling the intersecting roles of zinc and gliotoxin. Microbiology (Reading), 167 (11). pp. 1-15. ISSN 1465-2080 DOI: https://doi.org/10.1099/mic.0.001106

Saleh, AA and Jones, GW and Tinley, FC and Delaney, SF and Alabbadi, SH and Fenlon, K and Doyle, S and Owens, RA (2018) Systems impact of zinc chelation by the epipolythiodioxopiperazine dithiol gliotoxin in Aspergillus fumigatus: a new direction in natural product functionality. Metallomics, 10 (6). pp. 854-866. ISSN 1756-591X DOI: https://doi.org/10.1039/c8mt00052b

Dolan, SK and Bock, T and Hering, V and Owens, RA and Jones, GW and Blankenfeldt, W and Doyle, S (2017) Structural, mechanistic and functional insight into gliotoxin bis-thiomethylation in Aspergillus fumigatus. Open Biol, 7 (2). ISSN 2046-2441 DOI: https://doi.org/10.1098/rsob.160292

O'Keeffe, G and Hammel, S and Owens, RA and Keane, TM and Fitzpatrick, DA and Jones, GW and Doyle, S (2014) RNA-seq reveals the pan-transcriptomic impact of attenuating the gliotoxin self-protection mechanism in Aspergillus fumigatus. BMC genomics, 15. 15- 894. DOI: https://doi.org/10.1186/1471-2164-15-894

Owens, RA and Hammel, S and Sheridan, KJ and Jones, GW and Doyle, S (2014) A proteomic approach to investigating gene cluster expression and secondary metabolite functionality in Aspergillus fumigatus. PloS one, 9 (9). e106942 - ?. DOI: https://doi.org/10.1371/journal.pone.0106942

O'Hanlon, KA and Margison, GP and Hatch, A and Fitzpatrick, DA and Owens, RA and Doyle, S and Jones, GW (2012) Molecular characterization of an adaptive response to alkylating agents in the opportunistic pathogen Aspergillus fumigatus. Nucleic acids research, 40 (16). 7806 - 7820. ISSN 0305-1048 DOI: https://doi.org/10.1093/nar/gks522